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ARTICLE
Year : 2010  |  Volume : 15  |  Issue : 2  |  Page : 82-85

Autoimmune haemolytic anaemia and fever of undetermined origin as presenting manifestations of hodgkin disease: A case report


1 Dept of Paeditrics, College of Medicine, University of Nigeria/University of Nigeria Teaching Hospital, Enugu, Nigeria
2 Dept of Haematology, College of Medicine, University of Nigeria/University of Nigeria Teaching Hospital, Enugu, Nigeria
3 Dept of Morbid Anatomy, College of Medicine, University of Nigeria/University of Nigeria Teaching Hospital, Enugu, Nigeria

Correspondence Address:
S N Uwaezuoke
Department of Paediatrics, University of Nigeria Teaching Hospital, Enugu
Nigeria
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Source of Support: None, Conflict of Interest: None


DOI: 10.4314/jcm.v15i2.11

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Introduction: Autoimmune haemolytic anaemia is an important cause of acute or chronic anaemia. Its association with lymphoproliferative disorders such as non-Hodgkin lymphoma, and Hodgkin disease is well documented in the literature. Subjects and Methods: We report a 14 year-old male adolescent who presented with protracted recurrent fever, as well as clinical and laboratory findings suggestive of autoimmune haemolytic anaemia. Results: Patient however responded poorly to standard therapeutic interventions including steroids. Postmortem histology revealed Hodgkin disease (lymphocyte-depletion type) as the fundamental diseasea diagnosis not strongly considered before the patient 's death. Recommendations: We recommend a high index of suspicion for Hodgkin disease in any patient who presents with chronic haemolytic anaemia not responding satisfactorily to treatment even in the absence of peripheral lymphadenopathy.


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